ESMFold2

5-30 minutesPaperCodeNeed Code Links

Predicts protein, DNA, RNA, and ligand complexes

Readiness

Readiness: Need Code Links
Smoke: passed
Artifacts: passed
Production: need_code_esmfold2_modeling_architecture_or_compatible_transformers_release
Storage: code/runtime unresolved
Strategy: Await exact ESMFold2Model implementation or compatible Transformers release; Biohub/esm input utilities alone are insufficient for local inference.
Next: Find the public release/commit or source package containing the ESMFold2Model architecture compatible with biohub/ESMFold2-Fast, then cache the model and rerun a tiny fold validation.

2026-07-18T17:33:47+08:00 SOP large-tool batch: remains Need >5GB. Official Biohub ESMFold2 page provides local Hugging Face/Transformers usage and states code/model weights are released; backend has no ESMFold2 runtime/model cache/real adapter yet. Current runner is esmfold2-smoke placeholder. 2026-07-18T18:39:16+08:00 SOP Need >5GB active batch: Read-only audit confirmed Biohub ESMFold2 and ESMFold2-Fast are public Hugging Face models; license needs final model-card capture before promotion. Backend has no Biohub ESM runtime/model cache yet. 2026-07-18T19:02:14+08:00 SOP Need >5GB active install batch: Staged Biohub ESM repo at /media/nik/seagate_nik/bio_server/repos/biohub_esm and ESM site layer at /media/nik/seagate_nik/bio_server/envs/esmfold2_py312_site. Installed esm 3.3.0 and Transformers source 5.15.0.dev0, but both PyPI and current source Transformers lack `transformers.models.esmfold2`; AutoModel rejects model_type `esmfold2`. Exact local model architecture code or compatible release is missing, so local production validation cannot proceed. 2026-07-18T20:49:48+08:00 SOP targeted make-ready/reclassify batch: Confirmed status remains Need Code Links. Biohub ESM source and ESMFold2/Fast model identifiers are staged, but the required `transformers.models.esmfold2` / `ESMFold2Model` architecture is absent from the public/local Transformers stack tested here, so local inference cannot be production validated yet.